PAPERS


 

Garland BT, Boehm M, Grayson PC, St. Hilaire C, Brofferio A, Starnes BW. Abnormal molecular response to Takayasu arteritis causing extensive large-vessel calcification. J Vasc Surg Cases Innov Tech. 2016 Dec;2(4):190-192. PMID 28748225

Jin H°, St. Hilaire C°, Huang Y°, Yang D, Dmitrieva NI, Negro A, Schwartzbeck R, Liu Y, Yu Z, Walts A, et al. Increased activity of TNAP compensates for reduced adenosine production and promotes ectopic calcification in the genetic disease ACDC. Science Signaling. 2016;9(458):ra121-ra. PMID 27965423 °denotes equal contribution

Roman BL and St. Hilaire CCatching a Disease: A Molecular Trap as a Therapy for Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2016 Nov 1;194(9):1047-1049. PMID:27797615

St. Hilaire C, Liberman M, and Miller JD. Bidirectional Translation in Cardiovascular Calcification. Arterioscler Thromb Vasc Biol. 2016;36(3):e19-24. PMID: 26912744

Y. Liu, A.A. Jesus, B. Marrero, D. Yang, S.E. Ramsey, G.A. Montealegre Sanchez, K. Tenbrock, H. Wittkowski, O.Y. Jones, H.S. Kuehn, C-C.R. Lee, M.A. DiMattia, E.W. Cowen, B. Gonzalez, I. Palmer, J.J. DiGiovanna, A. Biancotto, H. Kim, W.L. Tsai, A.M. Trier, Y. Huang, D.L. Stone, S. Hill, H.J. Kim, C. St. Hilaire, S Gurprasad, N. Plass, D. Chapelle, I. Horkayne-Szakaly, D. Foell, A. Barysenka, F. Candotti, S.M. Holland, J.D. Hughes, H. Mehmet, A.C. Issekutz, M. Raffeld, J. McElwee, J.R. Fontana, C.P. Minniti, S. Moir, D.L. Kastner, M. Gadina, A.C. Steven, P.T. Wingfield, S.R. Brooks, S.D. Rosenzweig, T.A. Fleisher, Z. Deng, M. Boehm, A.S. Paller, and R. Goldbach-Mansky. Activated STING in a Vascular and Pulmonary Syndrome. N Engl J Med. 2014 Aug 7;371(6):507-18. PMID 25029335

CommentaryCrow YJ, and Casanova JL. STING-associated vasculopathy with onset in infancy–a new interferonopathy. N Engl J Med. 2014;371(6):568-71.

P. Lanzer, M. Boehm, V. Sorribas, M. Thiriet, J. Janzen, T. Zeller, C. St. Hilaire, C. Shanahan. Medial vascular calcification revisited: review and perspectives. Eur Heart J. 2014 Jun 14;35(23):1515-1525. PMID 24740885

B.C. Cooley, J. Nevado, J. Mellad, D. Yang, C. St. Hilaire, A. Negro, F. Fang, G. Chen, H. San, A. D. Walts, R. L. Schwartzbeck, B. Taylor, J. D. Lanzer, A. Wragg, A. Elagha, L. E. Beltran, C. Berry, R. Feil, R. Virmani, E. Ladich, J. C. Kovacic, M. Boehm. TGF-β Signaling Mediates Endothelial-to-Mesenchymal Transition (EndMT) During Vein Graft Remodeling. Sci Transl Med. 2014 Mar 12;6(227):227ra34. PMID 24622514.

Commentary: D. James, S. Rafii. Maladapted Endothelial Cells Flip the Mesenchymal Switch. Sci Transl Med. 2014 Mar 12;6(227):227fs12

St. Hilaire C°, Ziegler SGº, Markello T°, Bruscs A, Groden C, Gill F, Carlson-Donohoe H, Lederman RJ, Chen MY, Yang D, Siegenthaler MP, Arduino C, Mancini C, Freudenthal B, Stanescu HC, Zdebik AA, Krishna Chaganti R, Nussbaum R, Kleta R°, Gahl WAº, Boehm M°. NT5E Mutations and Arterial Calcifications. N Engl J Med. 2011 Feb 3;364(5):432-42. PMID 21288095  °denotes equal contribution

Correspondence: Boehm M., St. Hilaire C., Gahl W.A. NT5E mutations and Arterial Calcifications. N Engl J Med. 2011 364: 1577-1580

This paper was highlighted in 20+ articles, including:

Markello TC, Pak LK, St. Hilaire C, Dorward H, Ziegler SG, Chen MY, Chaganti K, Nussbaum RL, Boehm M, Gahl WA. Vascular pathology of medial arterial calcifications in NT5E deficiency: Implications for the role of adenosine in pseudoxanthoma elasticum. Mol Genet Metab. 2011 May;103:44-50. PMID 21371928

Correspondence: Markello T., Pak L.K., St. Hilaire C., Ziegler S., Nussbaum R., Boehm M., Gahl W.A. Reply to Professor Leftheriotis et al. Molecular Genetics and Metabolism. 2011 July;103(3): 305

Kovacic JC, Gupta R, Lee AC, Ma M, Fang F, Tolbert CN, Walts AD, Beltran LE, San H, Chen G, St. Hilaire C, Boehm M. Stat3-dependent acute Rantes production in vascular smooth muscle cells modulates inflammation following arterial injury in mice. J Clin Invest. 2010 Jan;120(1):303-14. PMID 20038813

Commentary: Hla T and Oo ML. Ramping up RANTES in the acute response to arterial injury J Clin Invest. 2010 Jan;120(1):90–92.

St. Hilaire C, Carroll SH, Chen H, Ravid K. Mechanisms of induction of adenosine receptor genes and its functional significance. J Cell Physiol. 2009 Jan;218(1):35-44. PMID 18767039

Nguyen HG, Makitalo M, Yang D, Chinnappan D, St. Hilaire C, Ravid K. Deregulated Auroa-B induced tetraploidy promotes tumorigenesis. FASEB J. 2009 Aug; 23(8):2741-8. PMID 19332642

St. Hilaire C, Yang D, Schreiber BM, Ravid K. B-Myb regulates the A(2B) adenosine receptor in vascular smooth muscle cells. J Cell Biochem. 2008 Apr 15;103(6):1962-74. PMID 17979185

St. Hilaire C, Koupenova M, Carroll SH, Smith BD, Ravid K. TNF-alpha upregulates the A2B adenosine receptor gene: The role of NAD(P)H oxidase 4. Biochem Biophys Res Commun. 2008 Oct 24;375(3):292-6. PMID18647598

Hurtado PA, Vora S, Sume SS, Yang D, St. Hilaire C, Guo Y, Palamakumbura AH, Schreiber BM, Ravid K, Trackman PC. Lysyl oxidase propeptide inhibits smooth muscle cell signaling and proliferation. Biochem Biophys Res Commun. 2008 Feb 1;366(1):156-61. PMID 18060869.

Yang D, McCrann DJ, Nguyen H, St. Hilaire C, DePinho RA, Jones MR, Ravid K. Increased polyploidy in aortic vascular smooth muscle cells during aging is marked by cellular senescence. Aging Cell. 2007 Apr;6(2):257-60. PMID 17291294

Yang D, Zhang Y, Nguyen HG, Koupenova M, Chauhan AK, Makitalo M, Jones MR, St. Hilaire C, Seldin DC, Toselli P, Lamperti E, Schreiber BM, Gavras H, Wagner DD, Ravid K. The A2B adenosine receptor protects against inflammation and excessive vascular adhesion. J Clin Invest 2006 July;116(7):1913-1923. PMID 16823489

Hazony Y, Lu J, St. Hilaire C, Ravid K. Hematopoietic gene promoters subjected to a group-combinatorial study of DNA samples: identification of a megakaryocytic selective DNA signature. Nucleic Acids Res. 2006 34(16):4416-28. PMID 16936310

Nagata Y, Jones MR, Nguyen HG, McCrann DJ, St. Hilaire C, Schreiber BM, Hashimoto A, Inagaki M, Earnshaw WC, Todokoro K, Ravid K. Vascular smooth muscle cell polyploidization involves changes in chromosome passenger proteins and an endomitotic cell cycle. Exp Cell Res. 2005 May 1;305(2):277-91. PMID 15817153

Al-Baradie R, Yamada K, St Hilaire C, Chan WM, Andrews C, McIntosh N, Nakano M, Martonyi EJ, Raymond WR, Okumura S, Okihiro MM, Engle EC. Duane radial ray syndrome (Okihiro syndrome) maps to 20q13 and results from mutations in SALL4, a new member of the SAL family. Am J Hum Genet. 2002 Nov; 71(5):1195-9. PMID: 12395297